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The Use And Misuse Of Nonsteroidal Anti-inflammatory Drugs (nsaids)
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2.6 DATA COLLECTION
a. Data collection form (Appendix V) was used to collect information about the prescribing pattern of NSAIDs in the Pharmacy Unit of General Outpatient Department (GOPD)- Family Medicine. Prescriptions, covering a period of six months between November 2013 and April 2014 were used for the study.
b. Trained research assistant were used to administer the pretested questionnaires (Appendix III) to eligible residents to elicit sociodemographic characteristics of the respondents and information on NSAIDs use.
c. Pharmacists in community practice were distributed self administered questionnaire (Appendix IV) to elicit information on their demographic information and dispensing characteristics of NSAIDs in their Pharmacy.
2.7 PRETESTING OF QUESTIONNAIRES
Twenty of Residents questionnaires (5%) ware pre-tested in Afon in Asa Local Government Area, a neighbouring town to Ilorin metropolis which is in the same state. Pre-testing will ensure the instrument could be used to measure intended items and able to produce reliable information which is reproducible on repeated use. It is also important to correct some question items which may be ambiguous to the respondents and could be interpreted differently by the respondents. The pre tested questionnaires were also analyzed and necessary amendments were done before administration to the intended respondents.
Five Pharmacists questionnaires were pretested in Offa, Offa Local Government of Area I Kwara state among the Community Pharmacists.
2.8 DATA ANALYSIS
The data from the questionnaires will be sorted and properly checked to ensure that the questionnaires were filled correctly and completely. Data will be coded and analyzed with the computer using the Statistical Package for Social Sciences (SPSS) software package version 16.
Analyzed data will be presented in form of frequency tables, percentages, graphs for descriptive statistic Chi-square and odd ratio from logistic regression were used to test for significant associations between categorical variables. P value less than 0.05 were adjudged significant in relevant situations.
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ABSRACT - [ Total Page(s): 1 ]ABSTRACT COMING SOON ... Continue reading---
CHAPTER ONE - [ Total Page(s): 16 ]TNF, originally termed "cachectin" because of its ability to produce a wasting syndrome, is composed of two closely related proteins: mature TNF (TNF-a) and lymphotoxin (TNF-b), both of which are recognized by the same cell-surface receptors. There are two types of TNF receptors, a 75-kd type 1 receptor and a 55-kd type 2 receptor. IL-1 and TNF produce many of the same proinflammatory responses. A naturally occurring IL-1 receptor antagonist (IL-1ra), competes with IL-1 for receptor binding, blo ... Continue reading---
CHAPTER THREE - [ Total Page(s): 8 ]CHAPTER THREE RESULTS3.1 RESULTS OF ANALYSIS OF PRESCRIPTIONS/TREATMENT SHEETSOut of 1497 prescription sheets 1297 prescriptions contained NSAIDs with total of 1392 NSAIDs. The prescribing rate was hence found to be 86.6%. 7.3% of prescriptions contained more than one NSAIDs. ... Continue reading---
CHAPTER FOUR - [ Total Page(s): 2 ]CHAPTER FOURDISCUSSIONStudy of the Prescribing pattern of Nonsteroidal Antiinflammatory Drugs indicated more number of females assess health care for pain and related conditions than their male counterpart (Table 3.1), although there is widespread assumption that women will consult more readily for all symptoms or conditions and that men will be more reluctant or will delay consulting may result in health care providers assuming that women have a lower level of symptom severity before deciding ... Continue reading---
CHAPTER FIVE - [ Total Page(s): 1 ]CHAPTER FIVE CONCLUSIONThe prescribing rate of NSAIDs was high. The prevalence of NSAIDs misuse by residents was high Ibuprofen was the most highly misused among the residents. Dispensing pattern of NSAIDs by Pharmacists appeared to agree with the choice of medication use among residents. Educational status, occupation, prior knowledge of medication use and dispensing pattern of Pharmacists are factors that can influence public choice of NSAIDs use. ... Continue reading---
REFRENCES - [ Total Page(s): 5 ]Slater DM, Zervou S, Thornton S. (2002). Prostaglandins and prostanoid receptors in human pregnancy and parturition. J. Soc. Gynecol. Investig. 9:118-124.Soleymani F, Ahmadizar A and Abdollahi MA(2013). Survey on the factors influencing the pattern of medicine's use: Concerns on irrational use of drugs. J Res Pharm Pract. 2(2), 59–63.Solomon SD, McMurray JJ, Pfeffer MA, Wittes J, Fowler R, Finn P, Anderson WF, Zauber A, Hawk E, Bertagnolli M (2005). Cardiovascular risk associated with c ... Continue reading---
