• HYPOLIPIDEMIC AND ANTIOXIDANT CAPACITY OF METHANOL LEAF EXTRACT OF KIGELIA AFRICANA IN ALLOXAN INDUCED DIABETIC ALBINO RATS


  • You can get the complete material / full content @ a service support fee of ₦4,500.00(10-USDT) only

    Download This Material Now !!

    • ABSRACT - [ Total Page(s): 1 ]Diabetic mellitus is a metabolic disorder resulting from a defect in insulin secretion , insulin action or both . The deficiency of insulin leads to chronic hyperglycemia with disturbances of carbohydrate , fats  and protein metabolism. Kigelia Africana is a sausage tree known to have medicinal values. The aim of this work is to evaluate the hypolipidemic and antioxidant capacity of the plant , methanol leaf extract of kigelia Africana which was used for the study. The leaves were ground into a powdered form , weighed  and soaked with 500ml of methanol for 72hours. It was filtered and the f ... Continue Reading

         

      TABLE OF CONTENTS - [ Total Page(s): 1 ]Title page Certification PageApproval pageDedicationAcknowledgement Abstract Table of contentCHAPTER ONE1.1 Background of study1.2 Statement of the problem1.3 Aim of the study1.4 Objectives of the studyCHAPTER TWOLITERATURE REVIEW2.1 General information 2.2 Origin and geographical distribution2.3 Scientific classification2.4 Medical benefits of kigelia Africana 2.4.1 Antibacterial and antifungal2.4.2 Alternative uses of kigelia Africana2.4.3 Chemical constituents of kigelia Africana 2.5 Alloxan2.5.1 Chemical structure of alloxan 2.5.2 Mechanism of alloxan2.5.3 Chemical properties of alloxan2. ... Continue Reading

         

      CHAPTER ONE - [ Total Page(s): 1 ]INTRODUCTION1.1 BACKGROUND OF STUDYDiabetes mellitus is a metabolic disorder resulting from a defect in insulin secretion, insulin action or both. Insulin deficiency in turn leads to chronic hyperglycemia with disturbances of carbohydrate, fat and protein metabolism (Kumar et al., 2011). During diabetes, failure of insulin-stimulated glucose uptake by fat and muscle cause glucose concentration in the blood to remain high, consequently glucose uptake by insulin independent tissue increases. Increased glucose flux both enhances oxidant production and impairs antioxidant defenses by multiple inte ... Continue Reading