The Antiplasmodial Activity Of Extracts Of Edible Mushroom: Agaricus Bisporus On Plasmodium Berghei In Albino Mice

Based on Duncan multiple range test, the mean parasites at 200mg/ml of the aqueous extract (112±1.75) on the first day do not significantly differ from the second day (101±1.13), but significantly differs from the third (54±1.03) and fourth day (37±0.84). With respect to the mean parasites at 200mg/ml of the alcoholic extract on the first day (100±0.33), based on Duncan multiple range test, the first day differs significantly from the second day (38±0.20), the second day however do not significantly differ from the third day (32±0.17) but differ from the fourth day (4±0.10).
Based on Duncan multiple range test, the mean parasite at 400mg/ml of the alcoholic extract on the first day (102±1.12) do not significantly differ from the second day (94±1.04a) and the third day (92±0.77) but significantly differ fourth day (34±0.25). With respect to the mean parasites at 400mg/ml of the aqueous on the first day, based on Duncan multiple range test, the first day (138±2.00) do not differ significantly from the second (134±1.93) but there was an increase in the third (201±1.58) and fourth day (213±1.73), hence differs significantly.
Based on Duncan multiple range test, the mean parasite at 5mg/ml of chloroquine (positive control) on the first day (78±0.21) significantly differ from the second day (9±0.16) and the third day (2±0.05). However, there was no significant difference between the second and third day.
Based on Duncan multiple range test, the mean parasite of the negative control on the first day (458±2.47) significantly differ from all other days. The second day (594±2.52) also differ significantly from the third day (1013±1.88) and fourth (1096±2.35), just as the third day differ significantly from the fourth (Table 8).