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Prevalence Study Of Hepatitis B (australian Antigen) Among Patients
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VIRAL REPLICATION
With
respect to replication of the HBV, the fundamental process of viral
infection is the expression of the viral replication cycle in a rost
cell. The steps for the infection process involving HBV usually include
the following:
Enter a host
- contact and enter susceptible cell.
- Replicate within the cell.
- Sprea d to adjacent cells.
- Cause cellular injury.
- Engender a host immune response
- Be either cleared from the body of the host, establish a presistnt infection , or kill the host.
- Be shed back into the environment (prexote it al; 2005).
VIRAL SPREAD
Mechanisms
of viral spread very, but the most roates include bloodstream. The
presence of viruses in the blood is called VIREAMA>HBV is spread
through blood, body secretion, needles, placenta as well as sexually.
This os to say that transmission as through parental routes. Therefore,
transmission of HBV can occur from person to person as a result of
transfer of blood by any prouder which breaks the skin or mucous members
HBV spread mainly parentally, in most cases seen in adults , HBs
(Australian Antigen) has been identified in almost every body fluid f
infected persons- saliva tears semen, cerebrospinal fluid, ascetic
fluid, breast milk synovial fluid, gastric juice, urine and rarely in
faces. This disease is, therefore, a major occupational hazard of
medical personnel. It is commonly seen in people who receive multiple
blood transfusion or blood product intravenous drug abusers, homosexuals
and the sexually promiscuous.
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ABSRACT - [ Total Page(s): 1 ]The prevalence of viral hepatitis B among patients in National Orthopedic Hospital Enugu was studied. The samples comprised that of men , woman and children 200 in numbers, all patient of orthopedic Hospital Enugu. Laboratory investigation done were this HBs tested which 110 patient out of the 200 patients tested positive, and liver function tests found abnormal in almost all the patients that tested positive to HBsAG routine test. The commonest clinical presentations were fever and jaundice ... Continue reading---