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Antibacterial Activity Of Three Types Of Medicated Soaps Of Starhyrococcus Aureus Form Wound Infections
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CHAPTER ONE
INTRODUCTION
According to pelage et al (1986)
antibacterial activity is the ability to either destroy bacteria or
inhibit their growth. This is significant with respects to the human
body in preventing sepsis and skin infections. Also Derland (1981)
states that medicated soap have the germicidal substance like
chloroxyhlenol potassium mercuric iodide, trichlorocarbanlide etc.
incorporated into them, in order to enhance their antibacterial
activity. These germicide substance are normally added in a specified
amount and percentage of the substance used are always stated on the
soapcase or inside the lesflet which certains the information on how to
use the soap for various purposes.
Anon (1964) states that soap may
be defined as a chemical compound resulting from the interaction of
fathy acids oil and caustic soda (alkali) possesing the characteristic
soap like properties of detergents, surface tension lowering wetting and
emulsifying power and gel formation. All fatty oils and fats. Are
mixtures of glycoside compounds (erters) of trihydric alcohol,
glycosides and some fatty acids such as plasmatic acid the chemistry of
soap manufacturing may be expressed the following equation which is know
as saponification (Anon (1964).
HzCocoG5H31)3 + Na 0H Naoco15H31 (zH31 + c3H5(oH)3
Palliation caustic sodium palurtate glycerion
Soda
Amon
(1964) further explain that a bactericidal soap cernirts existentially
of the following 0.1 to 3% weight based on the total weight of the soap.
0 to 10% by weight based on the total weight of the soap in a compound of formular
R –Co-N1-CH2C00H
CH3
Here R represents an alkyl or alkenye group of 8 to carbon atoms.
According
to Johnson (1978) antibacterial soap may include 2,4,4,trichloro 2,2
hydroxydiphenyl in an amount 0.05 to 5% by weight and at least one
phosphorus oxyacid. Phosphorus oxyacid salt phosphoric ester is
represented by
(R1(oCH,CH2)
R2
Where R1 in (8-20 alkyl, R2 is
hydrogen or methyl and is (1-10). R1 is the same group as R2 or H alkali
metal and n is H or alkali metal. Such a soap has a wide range of
antibacterial activities and marSykes
(1958) described sterilization as the complete destruction of all
living matters. In medical sense, it is often used in a restricted sense
to refer to the destruction of pathogenic organisms only.
According
to William (1979) wound is defined as disruption of cellular and
anatomic continuity while its healing is the restoration of continuity.
That biological procen can only be accomplished by regeneration, cell
proliferation and collage production which can be alleviated washing the
would surface especially with medicated soap which due to its concert
of pherolic compound help in keeping off organisms like staphylococcus
aureus escherichia coli and Pseudomonas aeruginosa always from the would
to a certain stage. Wound can also result when the operative barrier of
the skin is breached by traumatic invasion or whether it is caused by
trauma or internationally by surgery. The open area is susceptible to
microbial invasion and once a would has become infected pus form in the
injured area resulting to wound abbess.
Baker et al decried
antisepsis as the most convenient way of preventing infection usually by
inhibiting the growth of bacteria. And most disinfectant when suitably
diluted have the artixeptic action. Different method are employed for
the destruction of bacteria or for getting rid of them and those method
can be conveniently divided into chemical physical and mechanical
methods.
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ABSRACT - [ Total Page(s): 1 ]The antibacterial activity of three type of medicate soap on staphylococcus aureus isolated from wound infections was conducted. Fifty individual with would infection within the age range of 9-73 years were sampled. Swabsticks were used to collect specimens from wound infection. each swabstick was streaked separately over plates of nutrient and macconkey agar and later incubated at 370c. out of the fifty (50) individuals sampled 25(50%) were mostly infected with staphylococcus aureus followed by ... Continue reading---
