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Antimicrobial Effects Of Three Species Of Mangifera Indica
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There have been reports of increasing development of drug resistance among human pathogens as well as undesirable side effects of certain antimicrobial agents. It is therefore necessary to search for new agents that are better, cheaper and without side effects for treating infectious diseases especially in developing countries.
In this research study, three sub-species (Kerosene, German and Sheri) of Mangifera indica leaf extracts were examined to ascertain which has more antimicrobial effect against the test organisms.
The test organisms were Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli, they were standardized using 0.5 McFarland standard and assayed using the agar well diffusion method. There was no observed inhibition in the aqueous extract of the three sub-species, but the ethanolic extracts showed inhibition in varying concentrations.
The test organisms were all susceptible to the ethanolic extracts in this order: Staphylococcus aureus having the highest susceptibility, followed by Escherichia coli and then Pseudomonas aeruginosa.
The three mango sub-species were potent on the organisms, with German mango being the most active, it was followed by Kerosene mango before Sheri mango.
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TABLE OF CONTENTS - [ Total Page(s): 1 ]TITLE PAGE
APPROVAL PAGE
DEDICATION
ACKNOWLEDGEMENTS
ABSTRACT
TABLE OF CONTENTS
LIST OF TABLES
LIST OF FIGURES
CHAPTER ONE
1.0 INTRODUCTION
1.1 AIMS
1.2 JUSTIF ... Continue reading---
CHAPTER ONE - [ Total Page(s): 2 ]1.0 INTRODUCTION Continuous spread of infectious diseases is a major apprehension for health institutions, pharmaceutical companies and government think tanks all over the world. Failure of treatment, particularly with the current escalating trends of multi-drug resistance (MDR) to the available modern drugs or antibiotics among emerging and re-emerging bacterial pathogens leads to serious risks (Olasehinde et al., 2016). Around 1900, 80% of the drugs were derived from plants, however, in the ... Continue reading---
CHAPTER TWO - [ Total Page(s): 1 ]MATERIALS AND METHOD 2.0 Plant Materials Three varieties of Mangifera indica leaves were gotten from Nsukka area, Enugu state. The leaves were from species locally known as -Kerosene mango, -German mango, and -Sheri mango (sweet mango), respectively. The Sheri mango produces fruits smaller than the first two. 2.1 Preparation of plant materials The leaves were washed for dust with tap water and rinsed with distilled water. They were dried under shade (at room temperature) for 10 ... Continue reading---
CHAPTER THREE - [ Total Page(s): 1 ]3.1 RESULTS At the end of the research experiment, it was ascertained that the aqueous extracts of the three sub-species of Mangifera indica was not effective in causing inhibition in the three test organisms used. In the case of the ethanolic extract of the three sub-species, there was visible inhibition, which varied with the Mangifera sub-species and with the different organisms. The results of both the aqueous and ethanolic extracts are represented in Table 3.1 and 3.2 respectively. ... Continue reading---
CHAPTER FOUR - [ Total Page(s): 1 ]DISCUSSION AND CONCLUSION 4.1 DISCUSSION Several studies has suggested that extracts of various part of plant Mangifera indica L. show a protective effect on different human pathologies. In particular, this extract acts as scavenger of free radical and consequently may exhibit beneficial pharmacological effects in several pathologies in which oxidative stress plays a major role (Guiseppe et al., 2019). The basic parameters influencing the quality of an extract are plant parts used as a ... Continue reading---
REFRENCES - [ Total Page(s): 1 ]REFERENCES Abbasi, A. M., Guo, X., Fu, X., Zhou, L., Chen, Y., Zhu, Y., et al. (2015). Comparative Assessment of Phenolic Content and in Vitro Antioxidant Capacity in the Pulp and Peel of Mango Cultivars. Inter. J. Mol. Sci. 16: 13507-13527. Abdul Wadood, Ghufran, M., Babar Jamal, S.B., Naeem, M., Khan, A., Ghaffar, R. (2003). Phytochemical analysis of medicinal plants occurring in local area of Mardan. Biochemistry and Analy. Biochem. 2:144. Aguoru, C.U., Manyi, M., O ... Continue reading---
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TABLE OF CONTENTS - [ Total Page(s): 1 ]TITLE PAGE
APPROVAL PAGE
DEDICATION
ACKNOWLEDGEMENTS
ABSTRACT
TABLE OF CONTENTS
LIST OF TABLES
LIST OF FIGURES
CHAPTER ONE
1.0 INTRODUCTION
1.1 AIMS
1.2 JUSTIF ... Continue reading---
ABSRACT -- [Total Page(s) 1]
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ABSRACT -- [Total Page(s) 1]
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