• PHENOTYPIC DETECTION OF EXTENDED SPECTRUM BETA LACTAMASES PRODUCING ORGANISM AMONG GODFREY OKOYE UNIVERSITY STUDENTS


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    • ABSRACT - [ Total Page(s): 1 ]Extended-spectrum beta-lactamases (ESBL) are enzymes that confer resistance to most beta-lactam antibiotics, including penicillin, cephalosporin, and the aztreonams. The aim of this present study is to phenotypically identify and establish the presence of ESBL-producing organism among students in the university community. Within the University community of Godfrey Okoye University, Enugu, early morning urine samples of midstream-catch were collected into sterile bottles from sixty (60) students between ages 18 and 25years from the 2ndMay to 31st May. Thirty (30) male students and thirty (30) f ... Continue Reading

         

      CHAPTER ONE - [ Total Page(s): 4 ]FIG 1: CAZ……………………AMC……………………CTXPhenotypic confirmation of ESBL production using DDST(Afunwa, 2018).The image in FIG 1 shows an increased zones of inhibition indicating the presence of ESBL producing organism.1.6.2 ESBL EtestsESBL Etests have been developed in order to quantify the synergy between extended-spectrum cephalosporins and clavulanate. The Etests called CT/CTL, TZ/TZL and PM/PML are two-sided strips containing gradients of cefotaxime (CT), or ceftazidime (TZ) or cefepime (PM), either alon ... Continue Reading