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INTESTINAL SCHISTOSOMIASIS AND ITS POSSIBLE PREVENTION AND CONTROL
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- Contributor: mr-chris
- engagements: 141
- Case No: 602548pw
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ABSRACT - [ Total Page(s): 1 ]Schistosomiasis is a neglected tropical disease that ranks second only to malaria in terms of human suffering in the tropics and subtropics. Five species are known to infect man and there are currently over 240 million people infected worldwide. The cornerstone of control to date has been mass drug administration with 40 mg/kg of praziquantel but there are problems with this approach. Human and bovine vaccines are in various stages of development. Integrated control, targeting the life cycle, is the only approach that will lead to sustainability and future elimination.
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CHAPTER ONE - [ Total Page(s): 3 ]The disability-adjusted life years (DALYs) lost as a result of schistosomiasis was estimated to be 1.7 million.3,4 However, in estimating the DALYs, the case definition used for schistosomiasis was limited to infection and associated mortality from schistosomiasis, and excludes mortality from bladder cancer, cirrhosis, or colon cancer that may be related to the infection. Hence, only an average of 0.006 disability weights was used in the estimation.3 King re-estimated the DALYs associated with Schistosoma infection using the assumption that all past and present Schistosoma in ... Continue Reading
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ABSRACT - [ Total Page(s): 1 ]Schistosomiasis is a neglected tropical disease that ranks second only to malaria in terms of human suffering in the tropics and subtropics. Five species are known to infect man and there are currently over 240 million people infected worldwide. The cornerstone of control to date has been mass drug administration with 40 mg/kg of praziquantel but there are problems with this approach. Human and bovine vaccines are in various stages of development. Integrated control, targeting the life cycle, is the only approach that will lead to sustainability and future elimination.
... Continue Reading
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