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The Presence Of Hepatitis B Envelope Antibody In Patients Who Have Been Previously Screened For The Surface Antigen
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Diagnosis
of hepatitis is made by biochemical assessment of liver function.
Initial laboratory evaluation should include: total and direct
bilirubin, ALT (alanine transaminase,) AST (aspartate aminotransferase),
alkaline phosphatase, prothrombin time, total protein albumin,
globulin, complete blood count, and coagulation studies(Hollingeret
al.,2001). Diagnosis is confirmed by demonstration of specific antigens
and/or antibodies.
There is yet no treatment for acute HBV
infection, but it is a vaccine-preventable infection. Several vaccines
have been used in the prevention of this infection, the prominent ones
including Lamivudine, Adefovir, Dipivoxil, Famvir, FTC, Ritonavir,
Theradigm-HBV, Ganciclovir (Hadziyannis et al.,1999).
1.1 OBJECTIVES
Hepatitis
B virus infection is of global concern. More importantly, it is of
national concern as over 23 million Nigerians are infected with HBV. The
incidence of the infection in South-Western Nigeria is of no less
importance as the region is still ravaged with high cases of
immunization difficulties. Most texts have been on HBsAg, whereas other
markers are equally important.
The purpose of the this study, therefore, is
To
determine the presence of Hepatitis B envelope antibody in patients who
have been previously screened for the surface antigen.
To determine the class of individuals mostly affected.
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