• A Hospital Based Study Of Malaria
    [IN NDIEGORO COMMUNITY, ABA SOUTH L.G.A. ABIA STATE]

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    • CHAPTER 1 MALARIA
      INTRODUCTION:
      Malaria is a life-threatening disease of man caused by parasite of the genus Plasmodium, which is transmitted from person to person, through the bite of infected female Anopheles mosquitoes. It is a killer and debilitating disease and remains a formidable health and socio-economic problem in the world (Nebeet al, 2002). Jaine and Michael (1990) described it as the leading cause of death in the developing world. The World Health Report (2002) reported that about 90% of all malaria deaths in the world today occur in Africa, South of the Sahara. And that this is because majority of the infections in Africa are caused by Plasmodium falciparum, the most dangerous of the four human malaria parasites. Anopheles gambiae is the most effective malaria vector, the most widespread in Africa and the most difficult to control. Global estimate on morbidity and mortality resulting from malaria shows between 300-500 million clinical cases and between 1.5-2.7 million deaths attributed to malaria annually (Obi, 1997; Salako, 1997; WHO, 1998 and UNICEF, 2000), and an estimated one million people in Africa die from malaria each year and most of these are children under 5 years old and women in their first pregnancy (WHO, 2002; Sherman, 1998). NIH (2001) reported that the number of deaths from malaria are on the increase due to insecticide resistance, antimalarial resistance and environmental changes.
      The four important species of the parasite that cause this disease are Plasmodium falciparum.P. malariae, P ovaleand      P. vivax. Various species of the malaria parasites such as P.falciparum and P. malariaeare reported in Nigeria (Eneanya, 1998; Matur, et al, 2001). Anopheles gambiae, An. funestus and An. arabiensis have been implicated for malaria transmission in Nigeria with major impacts (Umaru et al, 1997). Scientific investigations revealed many pathological effects of malaria on man which include varying degrees of anaemia, splenic enlargement and various syndromes resulting from physiological and pathological involvements of certain organs like the brain, liver and the kidneys (Adams and Macgraith, 1985). Chukwuraet al (2003) described P. falciparummalaria as the most prevalent and virulent in Nigeria, capable of causing mental apathy, weakness and generally slowing down economic development; accounting for up to 98% of severe cases with significant mortality and morbidity (WHO, 2000). Malaria has been observed to keep people away from school or work thereby affecting;
      (i)    The amount they learn at school
      (ii)    The quantity of food they are able to grow and
      (iii)    The money they can earn (WHO, 1991). Salako (1996) and Cooker et al, (2001) reported that malaria accounts for over (600) six hundred deaths daily in Nigeria, especially in children less than five years of age in the rural, peri-urban and urban settlements; with high index of child mortality from the disease.
      Mbanugo and Ejims (2000) also reported that malaria is holoendemic in many countries and directly responsible for up to 10-25% of the infant mortality. Poor knowledge, attitude and practice (KAP) by our people in handling malaria seems to compound the issue of this disease in our various communities, particularly in AbiaState. Studies in Nsukka, Enugu state by Briegeret al (1997) and in a coastal area of Lagos state by Nebeet al (2002) confirmed that the perception of malaria by the inhabitants were not helpful. Many believe that malaria is caused by such factors as excessive heat, malnutrition, eating too much palm oil and other superstitious considerations. This poor malaria perception stimulated the present study ‘A study to determine the prevalence of malaria infection among members of Ndiegoro community, Aba South L.G.A., Abia State., attending hospital and to ascertain their management practices’. The outcome of the study is hopefully expected to disclose some strategies for eliminating or reducing to the barest minimum this health problem of man and enhancement of his health, generally.
      1.2    AIMS AND OBJECTIVES OF THE STUDY
      The aims and objectives of this study are;
      •    To determine the prevalence of malaria in the study area andto document the management practices by the people in the community.
      (ii)    Specific Objectives:
      These are:
      •    To determine the prevalence of malaria with regards to age and sex
      •    To identify the Plasmodium species prevalent in the study area
      •    To document the help-seeking behavior of the people
      •    To document the preventive measures adopted by the people
      •    To document the treatment methods by the people

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    • ABSRACT - [ Total Page(s): 1 ]ABSTRACTThe study surveyed the prevalence of malaria as well as management practices adpted in Ndiegoro community, Aba South L.G.A., Abia state between May and August 2009. Blood samples of 300 individuals who attended local hospital were examined using Giemsa stained thick and thin films, One hundred and fifty two (152) persons (51%) were infected with Plasmodiumfalciparum . The age group 0-5 years ( 74.3%) had the highest prevalence, while the age group 36-45 years ( 40.0%) recorded the lowest ... Continue reading---

         

      APPENDIX A - [ Total Page(s): 2 ]depends on sex. ... Continue reading---

         

      QUESTIONNAIRE - [ Total Page(s): 1 ]QUESTIONNAIRE                                                                                                                     NNAMDI AZIKIWE UNIVERSITY                                                            AWKA                                                            DEPARTMENT OF PA ... Continue reading---

         

      LIST OF TABLES - [ Total Page(s): 1 ]LI ST OF TABLES Table 1:    Age prevalence of malaria   Table 2:    Sex prevalence of m alaria    Table 3:    Help-seeking behaviour of the respondents    Table 4:    Preventive measures adopted    Table 5:    Methods of malaria treatments used    Table 6:    Educational background and method of treatment  ... Continue reading---

         

      LIST OF FIGURES - [ Total Page(s): 1 ]LIST OF FIGURESFigure 1:    Geographic Distribution of Malaria   Figure2:    The Life Cycle of Malaria    ... Continue reading---

         

      TABLE OF CONTENTS - [ Total Page(s): 1 ]TABLE OF CONTENTTitle page    Certification     Dedication    Acknowledgement     Table of content     List of tables   List of figures   Abstract   Chapter OneIntroduction    1.2Aims and objectives   Chapter TwoLiterature Review  2.1    Geographical distribution of malaria    2.2    Epidemiology of malaria   2.2.    Environmental factors   2.2.2    Vectorial factors   2.2.3    Host factors 2.3    Studies on the prevalences of malaria  2. ... Continue reading---

         

      CHAPTER TWO - [ Total Page(s): 5 ]sporozoites which migrate to the salivary gland of the mosquito (Good et al, 2001). Some of these sporozoites will be expelled into the vertebrate host as the mosquito takes a blood meal, and thus reinitiate the infection in the vertebrate host.Malaria can also be transmitted through blood transfusion from infected person or transplacentaly from pregnant mother to the fetus. However, transmission of this nature accounts for a negligible percentage.2.6    Pathogenesis and Pathology of MalariaM ... Continue reading---

         

      CHAPTER THREE - [ Total Page(s): 1 ]CHAPTER THREE3.0    Materials and methods3.1    The Study AreaThe study area is Ndiegoro, a semi-urban community in Aba South L.G.A. in AbiaState southeastern Nigeria. It is located between latitude 8o and 10oNof equator and longitude 8o and 10o E of the meridian. The vegetation is typically rainforest. The mean annual rainfall of about 2250 to 2500mm and mean annual temperature is 25 to 27oc with high relative humidity. The rainy season is observed from May to October while the dry season ... Continue reading---

         

      CHAPTER FOUR - [ Total Page(s): 2 ]CHAPTER FOUR4.0 RESULTSThe results showed that 153 patients were positive for malaria parasite out of the 300 sampled. Therefore the prevalence of malaria was found to be 51.0% for the period between May and August, 2009. The prevalence of malaria with regards to age groups were found to be statistically significant (p) yrs. (Table 1). It was also observed that all the malaria cases detected were infections of only P. falciparum. No cases of mixed infections were identified.More ma ... Continue reading---

         

      CHAPTER FIVE - [ Total Page(s): 2 ]CHAPTER FIVEDiscussion:Malaria is acknowledged to be by far the most important tropical parasitic disease causing great suffering and loss of lives (WHO, 1993).The days of labor lost, the cost of treatment of patients and the negative impact of the disease make malaria a major social economic burden (WHO, 1993).Results from the study indicate that more than half (51.0%) of the individuals examined were positive for malaria parasites in their blood.Table 1 shows the prevalence of malaria infectio ... Continue reading---

         

      CHAPTER SIX - [ Total Page(s): 2 ]CHAPTER 6 SUMMARY AND RECOMMENDATION6.1    SummaryThis research set out to determine the prevalence of malaria infection among members of Ndiegoro community, Aba South L.G.A., AbiaState, attending hospital and to ascertain their management practices.The prevalence of malaria parasites was done using both thick and thin blood film microscopy on those attending local hospitals. On the knowledge of management practices of the people, qualitative data was elicited using structured questionnaire. ... Continue reading---

         

      REFRENCES - [ Total Page(s): 4 ]Report of an Informal Consultation WHO, Geneva 8-9 June 2000. WHO/CDS/RBM/2001:281-8WHO (1998). Malaria: Know the facts, World Health Organization News Letter 13 (1): 6-7.WHO (1998).Examining blood for malaria parasites. Bench Aids for the Diagnosis of Malaria, 1-8 plates.World Health Organization.WHO (2000). Roll Back Malaria. Promise for Progress. Roll Back Malaria Cabinet Project, WHO Geneva, 4-6.WHO (2003a). The African Malaria Report 2003, Geneva, World Health Organization/United    Nati ... Continue reading---