• The Prevalence Of Malaria Seropositive And Seronegative Population Among Kwara State University
    [A CASE STUDY OF MALETE STUDENTS.]

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    • 1.2 Statement of problem
      Malaria infection is a major public health challenge for many countries in the world (especially developing countries e.g Nigeria) causing tremendous high rates of morbidity and mortality (Jennison, 2015). The Plasmodium falciparum species infections are responsible for the majority of the human severe malaria burden worldwide (Greenwood and Mutabingwa, 2002). This species is found worldwide in tropical and sub-tropical regions. It is estimated that every year approximately one million people are killed by species, especially in Nigeria where this species predominates (Greenwood and Mutabingwa, 2002; Abdel-gadir, 2015).
      This parasite causes a lot of harvoc to the body such as destruction of red blood cells, leading to the clinical signs and symptoms such as fever, flu-like, chills etc. diarrhea, and anemia and jaundice due to loss of red blood cells unless treated quickly the disease can kill within 24 hours (Wells et al., 2009). Methods used in order to prevent the spread of disease, or to protect individuals in areas where malaria is endemic, include prophylactic drugs, mosquito eradication and the prevention of mosquito bites (Kochar et al., 2009). The continued existence of malaria in an area requires a combination of high human population density, high mosquito population density and high rates of transmission from humans to mosquitoes and from mosquitoes to humans (Akinleye, 2009). If any of these is lowered sufficiently, the parasite will sooner or later disappear from community (Snow et al., 2005). Many states, communities, institutions, seeing an increasing number of imported malaria cases owing to extensive travel and migration and little or no information is available as regarding the seroprevalence of malaria parasite in Kwara State University, Malete. Hence the need for the seroprevalence study to estimate the proportion (percentage) of student who seropositive and those seronegative of malaria infection.
      1.3 Justification
      It has been established that people of all ages are affected by malaria infection in sub-saharan Africa, especially Nigeria which bear the heaviest burden of malaria attack which is either treated at home or in the hospital. Early recognition and appropriate treatment can go a long way in minimizing the outcome of the disease. Previously, WHO (2014) has advocated for the management of malaria infections in the homes, institutions, work place, campuses should be done before seeking help from any near by health out let. In the recent time WHO urges endemic countries and malaria partners to adopt diagnostic testing, treatment and surveillance for malaria (WHO, 2011). Endemic countries and stakeholders should ensure that every suspected malaria case is tested and that every confirmed case be treated with a quality-assured anti malarial drug, and that every malaria case be tracked in a surveillance system. Due to this it became necessary to verify and compare the relationship between practice, socio-economic demographic characteristics and malaria infection serology status. There is paucity of information or no previous data on the seropositive or seronegative  prevalence of malaria among Kwara State University, Malete students. Hence the significance of this research.
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    • ABSRACT - [ Total Page(s): 1 ]ABSTRACT HERE ... Continue reading---

         

      CHAPTER TWO - [ Total Page(s): 6 ]The two methods in routine use are light microscopy and rapid diagnostic tests (RTDs) (Giribaldi et al., 2004; WHO, 2008).a. Light microscopic test: this is the direct microscopic visualization of the parasite on the thick and thin blood smear of patients (WHO, 2010). However, the risk of false negative microscopy is higher if the patient has received a recent dose of an artemisinin derivative (Gobbi et al., 2005). Microscopy can be used for speciation and quantification of parasites ... Continue reading---

         

      CHAPTER THREE - [ Total Page(s): 4 ]MicroscopyPreparation of Thick Blood FilmsA drop of blood of each patients sample was placed at the centre of a clean microscope slide. The cover of each syringe needle was used to spread the blood drop in a circular motion to approximately a diameter of 0.4cm.The slides were allowed to air dry (Cheesbrough, 2006).Preparation of 5% Giemsa in Phosphate Buffer (pH 7.2)5gram of Giemsa powder was weighed using a weighing balance.0.41 gram of Na2HPO4 and 0.65 gram of KH2PO4 was also weigh ... Continue reading---

         

      CHAPTER FOUR - [ Total Page(s): 4 ]Hypothesis Two: The There is no significant difference in malaria seropositive individual among Kwara State University Students on the basis of academic status.Table 4.2 shows the calculated chi-square value of 1.98 at p > 0.05. Since the p-value is greater than 0.05, the null hypothesis which states that there is no significant difference in malaria seropositive individual among Kwara State University Students on the basis of academic status is accepted. This means that there is no significant ... Continue reading---

         

      CHAPTER FIVE - [ Total Page(s): 1 ]CHAPTER FIVE5.0 DISCUSSION, CONCLUSION AND RECOMMENDATIONSThis study determined the prevalence of malaria seropositive and seronegative population among Kwara State University, Malete students. Related literature review was made considering scholars explanation of the subject matter. Relevant data for the study was generated through laboratory experiment conducted by the researcher. Two research hypotheses were formulated and the hypotheses stated that (1) there is no significant difference in m ... Continue reading---

         

      REFRENCES - [ Total Page(s): 4 ]REFERENCESAbdel-Gadir, A.M. (2015). Dynamics of Drug-Resistant Plasmodium falciparum in Areas of Seasonal Malaria Transmission in Sudan. Journal of Sudan Biological Science. 2(2):23-29. Abdul-Raheem, I.S. and Parakoy, D.B. (2009). Factors affecting mothers’ health care seeking behaviour for childhood illnesses in a rural Nigerian setting. Early Child Development and Care. 179(5): 671 – 683.Aderamo, A. J. (2007). Transport and Socioeconomic Development in Kwara State, Nigeria. The N ... Continue reading---