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Psychology Impact Of Living With Sickle Cell Anaemia
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Sickle Cell Trait
The trait form
of· sickle cell disease has no clinical manifestations except under
extraordinary circumstances, during which the individual might
experience a crisis similar to that of 'the anemia victims. Thus,
symptomatology in sickle cell trait can be virtually obliterated by
avoiding those circumstances which would precipitate a crisis
conditional Sickle cell trait individuals may be incapacitated by (1)
conditions of extreme hypoxia, such as flying in an unpressurized
aircraft or with underwater swimming, (2) during anesthesia when anoxia
has inadvertently occurred, (3)occurrence of occasional severe
pneumonia, .and (4) extr.eme physical exercise.
Etiology
Sickle
cell disease, in both its forms, is a genetically acquired condition.
(Song, ibid) Inherited as an autosomal recessive ,pattern (Fraser 1966),
sickle cell anemia is the homogygo~s state of the abnormal hemoglobin S
gene. The mating of two persons with the sickle cell trait would imply a
25 per cent probability that each offspring will inherit two abnormal
genes (Hb-s) ,8 25 per cent probability that the offspring will inherit
two normal genes, and a 50 per cent probability that the offspring will
inherit one normal gene and one abnormal gene. In other words, based on
statistical calculation using 'a Mendelian model, (Fraser,ibid, Stern
and Sherwood 1966) a family consisting of four offsprihg will produce
one offspring having sickle cell anemia, one offspring that is free of
any sickle cell gene,and two offspring having one normal, and one
abnormal gene
The union between one person having sickle cell anemia
(the homogygous state of the abnormal hemoglobin S gene) and another
person free of a sickle cell gene, will produce'offspring having one
normal and one abnormal gene Sickle cell trait is the heterozygous state
of the abnormal hemoglobin S gene. The union between a person with the
sickle cell trait and a person free of the sickle 'eelI gene implies a
50 per cent probability that the offspring will have the sickle cell
trait, and. a 50 per cent probability that the offspring will be free of
the sickle cell gene
Inheritance Patterns of Sickle Cell Disease
Treatment
During
crisis situations, -treatment is largely supportive and symptomatic.
Oxygen administration and the use of analgesics and sedatives seem to be
somewhat effective in reducing the painful symptoms of the acute
sickling periods.
Management and care must extend beyond medical
treatment.Optimal nutrition, satisfactory dental and hygienic care, and
avoidance of "exposure to infection and crisis precipitating factors are
essential in the care of the individual during quiescent periods.
The
use "of urea has received considerable recent interest "in the
treatment of sickle cell anemia, and feasibility studies are currently
underway to determine the extent that urea is effective as a
prophylactiC measure in the prevention of crisis.- Unfortunately, no
treatment has been universally demonstrated or accepted as an effective
combatant of sickle cell disease.
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ABSRACT - [ Total Page(s): 1 ]This study sought the psychology impact of living with sickle cell anaemia, a study of Babcock University, Illishan Remo, Ogun State. The study adopted a descriptive survey design in conjunction with the convenience sampling technique to randomly select 100 students from all departments in the study area. Data collection was done through the use and administration of a questionnaire. The data generated were analyzed using simple percentage and frequency count with the aid of the software SPSS ve ... Continue reading---
