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INSILICO IDENTIFICATION 0F PUTATIVE DRUG TARGETS IN STAPHYLOCOCCUS AUREUS
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ABSRACT - [ Total Page(s): 1 ]Staphylococcus aureus is one of the most important and studies gram positive bacterial strains, which have a great potential to infect human being as well as other mammals. Staphylococcus aureus is a major cause of infections responsible for much life threatening diseases like toxic-shock syndrome, staphylococcal scarlet fever, meningitis, osteomyelitis etc. infection due to these strains are difficult to treat. This research work focused on the identification of drug target enzymes in staphylococcus aureus. These drug target enzymes development of the new antibiotic which can kill or suppress
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TABLE OF CONTENTS - [ Total Page(s): 1 ]TABLE OF CONTENTSTitle pageCertificationDedicationAcknowledgementAbstractTable of contentCHAPTER ONE Introduction CHAPTER TWO Material and methods CHAPTER THREEResult CHAPTER FOUR Discussion CHAPTER FIVE Conclusion References ... Continue Reading
CHAPTER ONE - [ Total Page(s): 3 ]The currently known targets of staphylococcus aureus include PBP (penicillin binding protein) of peptidoglycan biosynthesis pathway. Previously, beta-lactam antibiotics were knows to be effective against them, but due to production of altered form of PBP protein as well as beta-lactamase enzyme synthesis those drugs are not effective now, hence, our current study involves identifying targets apart from PBP(Hao et al., 2012). Another antibiotics prescribed is fluroquinolone. Fluroquinolone target DNA Gyrase A enzyme-essential for the replication, supercoiling of DNA. But according to Stephen et ... Continue Reading
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ABSRACT - [ Total Page(s): 1 ]Staphylococcus aureus is one of the most important and studies gram positive bacterial strains, which have a great potential to infect human being as well as other mammals. Staphylococcus aureus is a major cause of infections responsible for much life threatening diseases like toxic-shock syndrome, staphylococcal scarlet fever, meningitis, osteomyelitis etc. infection due to these strains are difficult to treat. This research work focused on the identification of drug target enzymes in staphylococcus aureus. These drug target enzymes development of the new antibiotic which can kill or suppress
... Continue Reading
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